| Long name: |
ALEXA FLUOR 488 Conjugated, Jarid1C Polyclonal Antibody |
| Also known as: |
Anti-Jarid1C PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Jarid1C |
| Specificity: |
This is a highly specific antibody against Jarid1C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Jarid1C/KDM5C |
| Gene ID Number: |
11184 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period, MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements, facial dysmorphism, seizures, thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3, Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) , Tissue specificity:br> |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
DXS1272E XE169 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Jarid1C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Jarid1C |
| Short name: |
Jarid1C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Jarid1C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11114 |
| Gene: |
KDM5C |
More about : KDM5C |
| Long gene name: |
lysine demethylase 5C |
| Synonyms gene: |
SMCX JARID1C MRX13 |
| Synonyms gene name: |
AT rich interactive domain 1C (RBP2-like) Smcy homolog, AT rich interactive domain 1C mental retardation, Jumonji, X-linked (mouse) jumonji, X-linked 13 lysine (K)-specific demethylase 5C |
| Locus: |
Xp11, 22 |
| Discovery year: |
1999-04-23 |
| GenBank acession: |
Z29650 |
| Entrez gene record: |
8242 |
| Pubmed identfication: |
7951230 8162017 19826449 |
| RefSeq identity: |
NM_004187 |
| Classification: |
X-linked mental retardation PHD finger proteins Lysine demethylases AT-rich interaction domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000021606 |
| Locus Specific Databases: |
KDM5C database at LOVD |