| Long name: |
Jarid1C Primary Polyclonal Antibody |
| Also known as: |
Jarid1C PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Jarid1C |
| Specificity: |
This is a highly specific antibody against Jarid1C |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Jarid1C/KDM5C |
| Gene ID number: |
11184 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period, MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements, facial dysmorphism, seizures, thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3, Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) , Tissue specificity:br> |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DXS1272E, Histone demethylase JARID1C, JmjC domain containing protein SMCX, Jumonji AT rich interactive domain 1C, Jumonji/ARID domain-containing protein 1C, KDM5C, KDM5C_HUMAN, Lysine K specic demethylase 5C, Lysine-specic demethylase 5C, MRXJ, MRXSCJ, MRXSJ, Protein SmcX, Protein Xe169, Selected cDNA on X, SmcX protein, Smcx homolog X chromosome, Smcy homolog X linked, XE169, Xe169 protein, Xe169 protein, rbp2 like protein, SmcX protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Jarid1C |
| Short name: |
Jarid1C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Jarid1C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11114 |
| Gene: |
KDM5C |
More about : KDM5C |
| Long gene name: |
lysine demethylase 5C |
| Synonyms gene: |
SMCX JARID1C MRX13 |
| Synonyms gene name: |
AT rich interactive domain 1C (RBP2-like) Smcy homolog, AT rich interactive domain 1C mental retardation, Jumonji, X-linked (mouse) jumonji, X-linked 13 lysine (K)-specific demethylase 5C |
| Synonyms: |
DXS1272E XE169 |
| Locus: |
Xp11, 22 |
| Discovery year: |
1999-04-23 |
| GenBank acession: |
Z29650 |
| Entrez gene record: |
8242 |
| Pubmed identfication: |
7951230 8162017 19826449 |
| RefSeq identity: |
NM_004187 |
| Classification: |
X-linked mental retardation PHD finger proteins Lysine demethylases AT-rich interaction domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000021606 |
| Locus Specific Databases: |
KDM5C database at LOVD |