| Long name: |
Biotin Conjugated, SART1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SART1 |
| Specificity: |
This is a highly specific antibody against SART1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SART1 |
| Gene ID number: |
9092 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both proteins have tumor rejection antigens, The SART1(259) protein is found to be essential for the recruitment of the tri snRNP to the pre spliceosome in the spliceosome assembly pathway, The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients, The two encoded proteins are thought to be involved in the regulation of proliferation, This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy, and the SART1(259) protein expressed in the cytosol of epithelial cancers, its full length sequence is not published yet, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, SART1 encodes two proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Ara1 Snu66 SNRNP110 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SART1 Conjugated |
| Short name: |
Conjugated, SART1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, squamous cellular carcinoma antigen recognized by T cells (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Ara1 and HOMS1 and SART1259 and SNRNP110 and Snu66, SART1 and IDBG-58125 and ENSG00000175467 and 9092, SART1 and IDBG-644324 and ENSBTAG00000003094 and 615704, Sart1 and IDBG-131415 and ENSMUSG00000039148 and 20227, nuclei, poly(A) RNA binding, this GO :0000387 and spliceosomal snRNP assembly and biological process this GO :0000398 and mRNA splicing, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0044822 : poly(A) RNA binding, this GO :0044822 : poly(A) RNA binding, via spliceosome and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0007050 and cell cycle arrest and biological process this GO :0015030 and Cajal body and cellular component this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045585 and positive regulation of cytotoxic T cell differentiation and biological process this GO :0071013 and catalytic step 2 spliceosome and cellular component this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, squamous cell carcinoma antigen recognized by T cells |
| Identity: |
10538 |
| Gene: |
SART1 |
More about : SART1 |
| Long gene name: |
squamous cell carcinoma antigen recognized by T-cells 1 |
| Synonyms gene name: |
squamous cell carcinoma antigen recognised by T cells squamous cell carcinoma antigen recognized by T cells 1 |
| Synonyms name: |
small nuclear ribonucleoprotein 110kDa (U4/U6, U5) |
| Locus: |
11q13, 1 |
| Discovery year: |
1999-01-29 |
| GenBank acession: |
AB006198 |
| Entrez gene record: |
9092 |
| Pubmed identfication: |
9449708 |
| Havana BLAST/BLAT: |
OTTHUMG00000166771 |