| Long name: |
Myosin VIIa Primary Polyclonal Antibody |
| Also known as: |
Myosin VIIa PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Myosin VIIa |
| Specificity: |
This is a highly specific antibody against Myosin VIIa |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
875-910/2215 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Myosin VIIa |
| Gene ID number: |
4647 |
| Swiss Prot: |
Q13402 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells, In the inner ear, In the retina, Involved in hair-cell vesicle trafficking of aminoglycosides, Motor protein that is a part of the functional network formed by USH1C, Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, Required for normal hearing, Their highly divergent tails bind to membranous compartments, USH1G, Unconventional myosins serve in intracellular movements, and in the regulation of opsin transport in retinal photoreceptors, morphogenesis and organization of cochlear hair cell bundles, plays an important role in differentiation, plays an important role in the renewal of the outer photoreceptor disks, which are known to induce ototoxicity (By similarity), which are then moved relative to actin filaments, Myosins are actin-based motor molecules with ATPase activity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DFNA11, MYO7A, MYOVIIA, MYU7A, NSRD2, USH1B, Unconventional myosin-VIIa, DFNB2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Myosin VIIa |
| Short name: |
Myosin VIIa Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Myosin VIIa (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2784 |
| Gene: |
DFNA11 |
More about : DFNA11 |
| Long gene name: |
myosin VIIA |
| Synonyms gene: |
USH1B DFNB2 |
| Synonyms gene name: |
myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) |
| Synonyms: |
NSRD2 MYO7A |
| Locus: |
11q13, 5 |
| Discovery year: |
1992-06-08 |
| GenBank acession: |
U39226 |
| Entrez gene record: |
4647 |
| Pubmed identfication: |
8884266 |
| RefSeq identity: |
NM_000260 |
| Classification: |
Myosins, class VII A-kinase anchoring proteins Deafness associated genes FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000152822 |
| Locus Specific Databases: |
Hereditary Hearing Loss Homepage Mutations of the Myosin VIIa Gene CCHMC-BMI &, UC Hearing Loss Mutation Database |