| Long name: |
DDX11 Primary Polyclonal Antibody |
| Also known as: |
DDX11 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DDX11 |
| Specificity: |
This is a highly specific antibody against DDX11 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DDX11 |
| Gene ID number: |
1663 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
B-cells, Binds to both single- and double-stranded DNA, EGF and IL1-beta-treated keratinocytes, Expressed in dividing cells and/or cells undergoing high levels of recombination, Expressed in keratinocyte growth factor-stimulated cells but not in serum, G2, Its unwinding activity requires a 5'-single-stranded region for helicase loading, May function during either S, No expression is seen in cells signaled to terminally differentiate, Possesses DNA-dependent ATPase and helicase activities, Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy, Required for normal sister chromatid cohesion, Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance, Stimulates the flap endonuclease activity of FEN1, The helicase activity is capable of displacing duplex regions up to 100 bp, This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, Very low expression seen in the brain, and pancreas, dATP, or M phase of the cell cycle, ovary, since flush-ended duplex structures do not support unwinding, small intestine, testis, the Ctf18-RFC (replication factor C) complex activities, thymus, to a lesser extent, which can be extended to 500 bp by RPA or the cohesion establishment factor, DNA helicase involved in cellular proliferation, Tissue specificity: Highly expressed in spleen |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CHL1 related helicase gene 1, CHL1-like helicase homolog, CHL1-related protein 1, CHLR1, DDX11_HUMAN, DEAD/H Asp Glu Ala Asp/His box polypeptide 11, DEAD/H box protein 11, Ddx11, KRG 2, KRG-2, KRG2, Keratinocyte growth factor regulated gene 2 protein, Keratinocyte growth factor-regulated gene 2 protein, Probable ATP dependent RNA helicase DDX11, Probable ATP-dependent RNA helicase DDX11, hCHLR1, CHL1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DDX11 |
| Short name: |
DDX11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DDX11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2736 |
| Gene: |
DDX11 |
More about : DDX11 |
| Long gene name: |
DEAD/H-box helicase 11 |
| Synonyms gene name: |
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S, cerevisiae CHL1-like helicase) DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| Synonyms: |
CHLR1 KRG2 CHL1 ChlR1 WABS |
| Synonyms name: |
CHL1-like helicase homolog (S, cerevisiae) |
| Locus: |
12p11, 21 |
| Discovery year: |
1995-12-11 |
| GenBank acession: |
U75969 |
| Entrez gene record: |
1663 |
| RefSeq identity: |
NM_030653 |
| Classification: |
DEAD-box helicases DNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000168435 |