| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DDX11 |
| Specificity: |
This antibody reacts specifically with DDX11 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DDX11 |
| Gene ID: |
1663 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
B-cells, Binds to both single- and double-stranded DNA, EGF and IL1-beta-treated keratinocytes, Expressed in dividing cells and/or cells undergoing high levels of recombination, Expressed in keratinocyte growth factor-stimulated cells but not in serum, G2, Its unwinding activity requires a 5'-single-stranded region for helicase loading, May function during either S, No expression is seen in cells signaled to terminally differentiate, Possesses DNA-dependent ATPase and helicase activities, Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy, Required for normal sister chromatid cohesion, Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance, Stimulates the flap endonuclease activity of FEN1, The helicase activity is capable of displacing duplex regions up to 100 bp, This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, Very low expression seen in the brain, and pancreas, dATP, or M phase of the cell cycle, ovary, since flush-ended duplex structures do not support unwinding, small intestine, testis, the Ctf18-RFC (replication factor C) complex activities, thymus, to a lesser extent, which can be extended to 500 bp by RPA or the cohesion establishment factor, DNA helicase involved in cellular proliferation, Tissue specificity: Highly expressed in spleen |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CHLR1 KRG2 CHL1 ChlR1 WABS |
| Also known as: |
DDX11 Polyclonal Antibody |
| Other name: |
Anti- DDX11 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DDX11 |
| Short name: |
Anti- DDX11 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, Antibody to DDX11 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2736 |
| Gene: |
DDX11 |
More about : DDX11 |
| Long gene name: |
DEAD/H-box helicase 11 |
| Synonyms gene name: |
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S, cerevisiae CHL1-like helicase) DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| Synonyms name: |
CHL1-like helicase homolog (S, cerevisiae) |
| Locus: |
12p11, 21 |
| Discovery year: |
1995-12-11 |
| GenBank acession: |
U75969 |
| Entrez gene record: |
1663 |
| RefSeq identity: |
NM_030653 |
| Classification: |
DEAD-box helicases DNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000168435 |