| Long name: |
FITC Conjugated, ETHE1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ETHE1 |
| Specificity: |
This is a highly specific antibody against ETHE1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human E1 |
| Gene ID number: |
23474 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
EE is an autosomal recessive disorder characterized by neurodevelopmental delay and regression, It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria, May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm, Suppresses p53-induced apoptosis by preventing nuclear localization of RELA, acrocyanosis, diarrhea, leading to death in the first decade of life, recurrent petechiae, Involvement in disease:Defects in ETHE1 are a cause of ethylmalonic encephalopathy (EE) , Probably plays an important role in metabolic homeostasis in mitochondria |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
YF13H12 HSCO |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ETHE1 Conjugated |
| Short name: |
FITC Conjugated, ETHE1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, ETHE1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23287 |
| Gene: |
ETHE1 |
More about : ETHE1 |
| Long gene name: |
ETHE1, persulfide dioxygenase |
| Synonyms gene name: |
ethylmalonic encephalopathy 1 |
| Locus: |
19q13, 31 |
| Discovery year: |
2003-12-15 |
| Entrez gene record: |
23474 |
| Pubmed identfication: |
19136963 |
| RefSeq identity: |
NM_014297 |
| Havana BLAST/BLAT: |
OTTHUMG00000182697 |