| Catalog number: | bs-7610R-Biotin |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | ETHE1 Antibody, Biotin Conjugated |
| Quantity: | 100ul |
| Related search: |
| Long name: | Biotin Conjugated, ETHE1 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ETHE1 |
| Specificity: | This is a highly specific antibody against ETHE1 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human E1 |
| Gene ID number: | 23474 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Mouse, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | EE is an autosomal recessive disorder characterized by neurodevelopmental delay and regression, It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria, May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm, Suppresses p53-induced apoptosis by preventing nuclear localization of RELA, acrocyanosis, diarrhea, leading to death in the first decade of life, recurrent petechiae, Involvement in disease:Defects in ETHE1 are a cause of ethylmalonic encephalopathy (EE) , Probably plays an important role in metabolic homeostasis in mitochondria |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | YF13H12 HSCO |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | ETHE1 Conjugated |
| Short name: | Conjugated, ETHE1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, ETHE1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 23287 |
| Gene: | ETHE1 | More about : ETHE1 |
| Long gene name: | ETHE1, persulfide dioxygenase |
| Synonyms gene name: | ethylmalonic encephalopathy 1 |
| Locus: | 19q13, 31 |
| Discovery year: | 2003-12-15 |
| Entrez gene record: | 23474 |
| Pubmed identfication: | 19136963 |
| RefSeq identity: | NM_014297 |
| Havana BLAST/BLAT: | OTTHUMG00000182697 |
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