| Long name: |
Cy7 Conjugated, SERPINA12 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SERPINA12 |
| Specificity: |
This is a highly specific antibody against SERPINA12 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SERPINA12/Vaspin |
| Gene ID number: |
145264 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A number of such serpins have been shown to target cysteine proteases, It may modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues, Most inhibitory serpins target chymotrypsin-like serine proteases, Most serpins control proteolytic cascades, SerpinA12, SerpinA12 / Vaspin is expressed in visceral adipose tissues, SerpinA12 / Vaspin may be the compensatory molecule in the pathogenesis of metabolic syndrome and SerpinA12 / Vaspin recombinant protein or vaspin-mimicking agents such as vaspin analogs, Some serpins inhibit other classes of protease, These enzymes are defined by the presence of a nucleophilic serine residue in their catalytic site, These enzymes differ from serine proteases in that they are defined by the presence of a nucleophilic cysteine residue, Vaspin, Visceral adipose tissue-derived serine protease inhibitor, Visceral adipose-specific serpin and SERPINA12, also known as OL-64, but instead perform diverse functions such as storage (ovalbumin, certain serpins do not inhibit enzymes, cortisol-binding globulin) and tumor suppressor genes (maspin), hormone carriage proteins (thyroxine-binding globulin, in egg white), in their catalytic site, is a secreted protein which belongs to the serpin family, or small molecule agents may be the link to drug discovery and development, rather than a serine residue, May modulates insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues, Serpins are the largest and most diverse family of protease inhibitors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
OL-64 Vaspin |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
SERPINA12 Conjugated |
| Short name: |
Conjugated, SERPINA12 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, SERPINA12 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18359 |
| Gene: |
SERPINA12 |
More about : SERPINA12 |
| Long gene name: |
serpin family A member 12 |
| Synonyms gene name: |
antitrypsin), antitrypsin), clade A (alpha-1 antiproteinase, clade A (alpha-1 antiproteinase, member 12 , member 12 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor |
| Locus: |
14q32, 13 |
| Discovery year: |
2004-05-21 |
| GenBank acession: |
AY177692 |
| Entrez gene record: |
145264 |
| Pubmed identfication: |
24172014 |
| RefSeq identity: |
NM_173850 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000171349 |