| Long name: |
ALEXA FLUOR 594 Conjugated, Lipin 1 Polyclonal Antibody |
| Also known as: |
Anti-Lipin 1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Lipin 1 |
| Specificity: |
This is a highly specific antibody against Lipin 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lipin 1 |
| Gene ID Number: |
23175 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Mouse |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism, LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels, LPIN1 selectively activates a subset of PGC1 alpha target pathways, Lipin 2 and Lipin 3, This family contains three members: Lipin 1, a heterogeneous group of disorders characterized by loss of body fat, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain, all of which contain a nuclear signal sequence, fatty liver, hypertriglyceridemia and insulin resistance, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha, resulting in insulin resistance and lipodystrophy, whereas a deficiency in LPIN1 may deter normal adipose tissue development, Lipin 1 is a member of the Lipin family of nuclear proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0188 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Lipin 1 |
| Short name: |
Lipin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Lipin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13345 |
| Gene: |
LPIN1 |
More about : LPIN1 |
| Long gene name: |
lipin 1 |
| Locus: |
2p25, 1 |
| Discovery year: |
2001-01-24 |
| GenBank acession: |
D80010 |
| Entrez gene record: |
23175 |
| Pubmed identfication: |
11138012 8724849 16950137 |
| RefSeq identity: |
NM_145693 |
| Classification: |
Lipins |
| Havana BLAST/BLAT: |
OTTHUMG00000119082 |