| Long name: |
ALEXA FLUOR 647 Conjugated, SP3 Polyclonal Antibody |
| Also known as: |
Anti-SP3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SP3 |
| Specificity: |
This is a highly specific antibody against SP3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SP3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus, Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes, Sp transcription factors share similar structures but do not share simi-lar functions, Sp1, Sp1, Sp1 and Sp3, Sp2, Sp2 and Sp3 are ubiquitously expressed, Sp2 only weakly binds to GT boxes, Sp3 (SPR-2) and Sp4 (SPR-1), Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not, Sp3 is the only Sp member to inhibit Sp1 and Sp4 media, a regulatory element for the â, but not Sp2 or Sp4, interact with E2, while Sp4 is abundantly expressed in brain with limited expression in other tissues, &circ, «, 4 subunit of neuronal nicotinic acetylcholine receptors, The Sp transcription factor family includes Sp1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
SPR-2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SP3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
SP3 |
| Short name: |
SP3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Sp3 transcription factor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0016605 and PML body and cellular component this GO :0017053 and transcriptional repressor complex and cellular component this GO :0030183 and B cell differentiation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030218 and erythrocyte differentiation and biological process this GO :0030219 and megakaryocyte differentiation and biological process this GO :0030224 and monocyte differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030851 and granulocyte differentiation and biological process this GO :0043353 and enucleate erythrocyte differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048596 and embryonic camera-type eye morphogenesis and biological process this GO :0048706 and embryonic skeletal system development and biological process this GO :0060136 and embryonic process involved in female pregnancy and biological process this GO :0060216 and definitive hemopoiesis and biological process, SP3 and IDBG-640536 and ENSBTAG00000000176 and 540766, SP3 and IDBG-75293 and ENSG00000172845 and 6670, SPR2, Sp3 and IDBG-179756 and ENSMUSG00000027109 and 20687, metal ion binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000987 and core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001503 and ossification and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001779 and natural killer cell differentiation and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0001889 and liver development and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000987 : core promoter proximal region sequence-specific DNA binding and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding, this GO :0000987 : core promoter proximal region sequence-specific DNA binding, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003690 : double-stranded DNA binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, Sp3 transcription factor |
| Identity: |
11208 |
| Gene: |
SP3 |
More about : SP3 |
| Long gene name: |
Sp3 transcription factor |
| Locus: |
2q31, 1 |
| Discovery year: |
1993-02-10 |
| GenBank acession: |
M97191 |
| Entrez gene record: |
6670 |
| Pubmed identfication: |
1341900 1454515 |
| RefSeq identity: |
NM_003111 |
| Classification: |
Sp transcription factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000132333 |