| Long name: |
ALEXA FLUOR 350 Conjugated, Claudin 2 Polyclonal Antibody |
| Also known as: |
Anti-Claudin 2 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Claudin 2 |
| Specificity: |
This is a highly specific antibody against Claudin 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Claudin 2 |
| Gene ID Number: |
9075 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Able to form homopolymers of heteropolymers with other claudin family members, Claudin-2, Overexpression of claudin-2 is associated with a variety of diseases, The gene encoding claudin-2 maps to human chromosome X, also known as CLDN2 or SP82, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space, colorectal cancer, further affirming the importance of claudin-2 in cell adhesion, gastrointestinal carcinomas and inflammatory bowel disease, including lung cancer, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily, which contains nearly 153 million base pairs and houses over 1, 000 genes, The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Claudin 2 |
| Short name: |
Claudin 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Claudin 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2041 |
| Gene: |
CLDN2 |
More about : CLDN2 |
| Long gene name: |
claudin 2 |
| Locus: |
Xq22, 3 |
| Discovery year: |
1998-11-19 |
| GenBank acession: |
AK075405 |
| Entrez gene record: |
9075 |
| Pubmed identfication: |
9892664 |
| Classification: |
Claudins |
| Havana BLAST/BLAT: |
OTTHUMG00000022154 |
| Locus Specific Databases: |
Mental Retardation database |