| Long name: |
ALEXA FLUOR 555 Conjugated, Claudin 1 Polyclonal Antibody |
| Also known as: |
Anti-Claudin 1 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Claudin 1 |
| Specificity: |
This is a highly specific antibody against Claudin 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
185-211/211 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse Claudin 1 |
| Gene ID Number: |
12737 |
| Swiss Prot: |
O88551 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin, Often, Required for normal water homeostasis and to prevent excessive water loss through the skin, While some claudin family members play essential roles in the formation of impermeable barriers, and this determines the overall permeability, others mediate the permeability to ions and small molecules, probably via an indirect effect on the expression levels of other proteins, several claudin family members are coexpressed and interact with each other, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions, Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
SEMP1 ILVASC |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
Claudin 1 |
| Short name: |
Claudin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, Claudin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2032 |
| Gene: |
CLDN1 |
More about : CLDN1 |
| Long gene name: |
claudin 1 |
| Synonyms name: |
senescence-associated epithelial membrane protein 1 |
| Locus: |
3q28 |
| Discovery year: |
1998-11-19 |
| GenBank acession: |
AF101051 |
| Entrez gene record: |
9076 |
| Pubmed identfication: |
10828592 9892664 |
| RefSeq identity: |
NM_021101 |
| Classification: |
Claudins |
| Havana BLAST/BLAT: |
OTTHUMG00000156214 |