Long name: |
Cy3 Conjugated, Supervillin Polyclonal Antibody |
Category: |
Conjugated Primary Antibodies |
Conjugation: |
cy3 conjugation kit |
Host Organism: |
Rabbit (Oryctolagus cuniculus) |
Target Antigen: |
Supervillin |
Specificity: |
This is a highly specific antibody against Supervillin |
Modification: |
Unmodified |
Modification site: |
None |
Clonality: |
Polyclonal |
Clone: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Immunogen_range: |
80-130/2214 |
Subcellular location: |
Cell membrane |
Source: |
KLH conjugated synthetic peptide derived from human Supervillin |
Gene ID number: |
6840 |
Swiss Prot: |
O95425 |
Tested applications: |
IF(IHC-P) |
Recommended dilutions: |
IF(IHC-P)(1:50-200) |
Crossreactivity: |
Mouse, Rat, Human |
Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Antigen background: |
Appears to be involved in myosin II assembly, Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation, Isoform 2 may be involved in modulation of focal adhesions, May modulate myosin II regulation through MLCK during cell spreading, May play a role in invadopodial function, Plays a role in cytokinesis through KIF14 interaction (By similarity), Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6, an initial step in cell migration, Forms a high-affinity link between the actin cytoskeleton and the membrane |
Purification method: |
This antibody was purified via Protein A |
Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
Excitation Emission: |
512, 550nm/570, 615nm |
Synonyms: |
Archvillin, SVIL, p205/p250, Supervillin |
Properties: |
1 of the Supervillin Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
Gene target: |
Supervillin Conjugated |
Short name: |
Conjugated, Supervillin Antibody |
Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
Label: |
Cy3 |
Alternative name: |
cyanine 3 coupled, Supervillin (Antibody to) |
Alternative technique: |
antibodies |