| Long name: |
FITC Conjugated, CARD8 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CARD8 |
| Specificity: |
This is a highly specific antibody against CARD8 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CARD8 |
| Gene ID number: |
22900 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
May be a component of the inflammasome, May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases, a protein complex which also includes PYCARD, Inhibits NF-kappa-B activation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
TUCAN KIAA0955 CARDINAL NDPP Dakar |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CARD8 Conjugated |
| Short name: |
FITC Conjugated, CARD8 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, member 8 (Antibody to), caspase recruitment domain family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARD8 and IDBG-60120 and ENSG00000105483 and 22900, CARDINAL and DACAR and DAKAR and NDPP and NDPP1 and TUCAN, member 8, nuclei, protein homodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0032089 and NACHT domain binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0072559 and NLRP3 inflammasome complex and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0032089 : NACHT domain binding and also this GO :0042803 : protein homodimerization activity, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0032089 : NACHT domain binding, this GO :0042803 : protein homodimerization activity, caspase recruitment domain family |
| Identity: |
17057 |
| Gene: |
CARD8 |
More about : CARD8 |
| Long gene name: |
caspase recruitment domain family member 8 |
| Synonyms gene name: |
caspase recruitment domain family, member 8 |
| Locus: |
19q13, 33 |
| Discovery year: |
2003-12-03 |
| GenBank acession: |
AB023172 |
| Entrez gene record: |
22900 |
| Pubmed identfication: |
10231032 11408476 |
| RefSeq identity: |
NM_014959 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165047 |