| Long name: |
CARD8 Primary Polyclonal Antibody |
| Also known as: |
CARD8 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CARD8 |
| Specificity: |
This is a highly specific antibody against CARD8 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD8 |
| Gene ID number: |
22900 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
May be a component of the inflammasome, May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases, a protein complex which also includes PYCARD, Inhibits NF-kappa-B activation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Apoptotic protein NDPP1, CARD 8, CARD inhibitor of NF kappa B activating ligand, CARD inhibitor of NF kappaB activating ligand, CARD inhibitor of NF kappaB activating ligands, CARD-inhibitor of NF-kappa-B-activating ligand, CARD8, CARD8_HUMAN, CARDINAL, Caspase recruitment domain containing protein 8, Caspase recruitment domain family member 8, Caspase recruitment domain protein 8, Caspase recruitment domain-containing protein 8, DACAR, NDPP 1, NDPP1, TUCAN, Tumor up regulated CARD containing antagonist of CASP9, Tumor up regulated CARD containing antagonist of caspase 9, Tumor up-regulated CARD-containing antagonist of CASP9, Tumor upregulated CARD containing antagonist of CASP9, Apoptotic protein NDPP 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CARD8 |
| Short name: |
CARD8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 8 (Antibody to), caspase recruitment domain family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARD8 and IDBG-60120 and ENSG00000105483 and 22900, CARDINAL and DACAR and DAKAR and NDPP and NDPP1 and TUCAN, member 8, nuclei, protein homodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0032089 and NACHT domain binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0072559 and NLRP3 inflammasome complex and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0032089 : NACHT domain binding and also this GO :0042803 : protein homodimerization activity, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0032089 : NACHT domain binding, this GO :0042803 : protein homodimerization activity, caspase recruitment domain family |
| Identity: |
17057 |
| Gene: |
CARD8 |
More about : CARD8 |
| Long gene name: |
caspase recruitment domain family member 8 |
| Synonyms gene name: |
caspase recruitment domain family, member 8 |
| Synonyms: |
TUCAN KIAA0955 CARDINAL NDPP Dakar |
| Locus: |
19q13, 33 |
| Discovery year: |
2003-12-03 |
| GenBank acession: |
AB023172 |
| Entrez gene record: |
22900 |
| Pubmed identfication: |
10231032 11408476 |
| RefSeq identity: |
NM_014959 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165047 |