| Long name: |
Cy5, 5 Conjugated, CARD8 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CARD8 |
| Specificity: |
This is a highly specific antibody against CARD8 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CARD8 |
| Gene ID number: |
22900 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
May be a component of the inflammasome, May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases, a protein complex which also includes PYCARD, Inhibits NF-kappa-B activation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
TUCAN KIAA0955 CARDINAL NDPP Dakar |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
CARD8 Conjugated |
| Short name: |
Conjugated, CARD8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, member 8 (Antibody to), 5 coupled, caspase recruitment domain family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARD8 and IDBG-60120 and ENSG00000105483 and 22900, CARDINAL and DACAR and DAKAR and NDPP and NDPP1 and TUCAN, member 8, nuclei, protein homodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0032089 and NACHT domain binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0072559 and NLRP3 inflammasome complex and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0032089 : NACHT domain binding and also this GO :0042803 : protein homodimerization activity, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0032089 : NACHT domain binding, this GO :0042803 : protein homodimerization activity, caspase recruitment domain family |
| Identity: |
17057 |
| Gene: |
CARD8 |
More about : CARD8 |
| Long gene name: |
caspase recruitment domain family member 8 |
| Synonyms gene name: |
caspase recruitment domain family, member 8 |
| Locus: |
19q13, 33 |
| Discovery year: |
2003-12-03 |
| GenBank acession: |
AB023172 |
| Entrez gene record: |
22900 |
| Pubmed identfication: |
10231032 11408476 |
| RefSeq identity: |
NM_014959 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165047 |