| Long name: |
PRMT5 Primary Polyclonal Antibody |
| Also known as: |
PRMT5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PRMT5 |
| Specificity: |
This is a highly specific antibody against PRMT5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRMT5 |
| Gene ID number: |
10419 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
May be part of a pathway that is connected to a chloride current, May play a role in cytokine-activated transduction pathways, May regulate the SUPT5H transcriptional elongation properties, Methylates RPS10, Methylates SUPT5H, Methylates histone H2A and H4 'Arg-3' during germ cell development, Methylates histone H3 'Arg-8', Methylates the Piwi proteins (PIWIL1, Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro, Negatively regulates cyclin E1 promoter activity and cellular proliferation, PIWIL2 and PIWIL4), Plays a role in the assembly of snRNP core particles, Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage, possibly through cytoskeletal rearrangement, such methylation being required for the assembly and biogenesis of snRNP core particles, which may repress transcription, with a preference for the formation of MMA, Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
72 kDa ICln-binding protein, ANM5_HUMAN, HMT1 hnRNP methyltransferase like 5, HOMOLOG OF, HRMT1L5, Histone-arginine N-methyltransferase PRMT5, IBP72, JBP 1, JBP1, Jak-binding protein 1, POMBE, POMBE HOMOLOG OF, PRMT 5, PRMT5, Protein arginine N methyltransferase 5, Protein arginine N-methyltransferase 5, Protein arginine methyltransferase 5, S, S, SHK1 KINASE BINDING PROTEIN 1, SHK1 KINASE-BINDING PROTEIN 1, SKB 1, SKB1, SKB1, SKB1, SKB1 homolog, SKB1: SKB1 homolog S, SKB1Hs, Shk1 kinase binding protein 1 homolog, Shk1 kinase-binding protein 1 homolog, pombe, 72 kDa ICln binding protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PRMT5 |
| Short name: |
PRMT5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PRMT5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10894 |
| Gene: |
PRMT5 |
More about : PRMT5 |
| Long gene name: |
protein arginine methyltransferase 5 |
| Synonyms gene: |
HRMT1L5 SKB1 |
| Synonyms gene name: |
pombe) , pombe) homolog SKB1 homolog (S, skb1 (S |
| Synonyms: |
SKB1Hs |
| Locus: |
14q11, 2 |
| Discovery year: |
1999-06-18 |
| GenBank acession: |
AF015913 |
| Entrez gene record: |
10419 |
| Pubmed identfication: |
9843966 |
| Classification: |
Protein arginine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000028709 |