| Long name: |
FITC Conjugated, AKAP5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AKAP5 |
| Specificity: |
This is a highly specific antibody against AKAP5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human AKAP5 |
| Gene ID number: |
9495 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), Members of this family, Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell, This family of proteins has been designated A-kinase anchoring proteins (AKAP) (1-3), To maintain this specific localization, and the DNA binding AKAP 95, display differential tissue specificity and localization (4-6), including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins, which are a network of proteins located on the internal surfaces of excitatory synapses, The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
AKAP75 AKAP79 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AKAP5 Conjugated |
| Short name: |
FITC Conjugated, AKAP5 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, AKAP5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
375 |
| Gene: |
AKAP5 |
More about : AKAP5 |
| Long gene name: |
A-kinase anchoring protein 5 |
| Synonyms gene name: |
A kinase (PRKA) anchor protein 5 |
| Locus: |
14q23, 3 |
| Discovery year: |
1999-09-16 |
| GenBank acession: |
M90359 |
| Entrez gene record: |
9495 |
| Pubmed identfication: |
1512224 1618839 |
| Classification: |
A-kinase anchoring proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000029634 |