| Long name: |
Biotin Conjugated, AKAP5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AKAP5 |
| Specificity: |
This is a highly specific antibody against AKAP5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human AKAP5 |
| Gene ID number: |
9495 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), Members of this family, Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell, This family of proteins has been designated A-kinase anchoring proteins (AKAP) (1-3), To maintain this specific localization, and the DNA binding AKAP 95, display differential tissue specificity and localization (4-6), including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins, which are a network of proteins located on the internal surfaces of excitatory synapses, The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
AKAP75 AKAP79 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AKAP5 Conjugated |
| Short name: |
Conjugated, AKAP5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, AKAP5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
375 |
| Gene: |
AKAP5 |
More about : AKAP5 |
| Long gene name: |
A-kinase anchoring protein 5 |
| Synonyms gene name: |
A kinase (PRKA) anchor protein 5 |
| Locus: |
14q23, 3 |
| Discovery year: |
1999-09-16 |
| GenBank acession: |
M90359 |
| Entrez gene record: |
9495 |
| Pubmed identfication: |
1512224 1618839 |
| Classification: |
A-kinase anchoring proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000029634 |