| Long name: |
ALEXA FLUOR 488 Conjugated, Fibrinogen gamma chain Antibody |
| Also known as: |
Anti-Fibrinogen gamma chain PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Fibrinogen gamma chain |
| Specificity: |
This is a highly specific antibody against Fibrinogen gamma chain |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
171-190/453 |
| Subcellular location: |
Helical, Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen gamma chain |
| Gene ID Number: |
2266 |
| Swiss Prot: |
P02679 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway, Fibrin deposition is also associated with infection, Has a major function in hemostasis as one of the primary components of blood clots, However, In addition, Maternal fibrinogen is essential for successful pregnancy, May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways, Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization, polymerizes to form an insoluble fibrin matrix, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo, where it protects against IFNG-mediated hemorrhage, Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Fibrinogen gamma chain Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Fibrinogen gamma chain |
| Short name: |
Fibrinogen gamma chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Fibrinogen g epitope (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3694 |
| Gene: |
FGG |
More about : FGG |
| Long gene name: |
fibrinogen gamma chain |
| Synonyms gene name: |
fibrinogen, gamma polypeptide |
| Locus: |
4q32, 1 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2266 |
| RefSeq identity: |
NM_021870 |
| Classification: |
Endogenous ligands Fibrinogen C domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150329 |
| Locus Specific Databases: |
A Database For Human Fibrinogen Variants LRG_585 |