| Long name: |
Biotin Conjugated, HRH2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HRH2 |
| Specificity: |
This is a highly specific antibody against HRH2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
160-180/359 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human HRH2 |
| Gene ID number: |
3274 |
| Swiss Prot: |
P25021 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also appears to regulate gastrointestinal motility and intestinal secretion, Possible role in regulating cell growth and differentiation, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity), through a separate G protein-dependent mechanism, The H2 subclass of histamine receptors mediates gastric acid secretion |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HRH2 Conjugated |
| Short name: |
Conjugated, HRH2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, histamine receptor H2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
H2R, HRH2 and IDBG-58464 and ENSG00000113749 and 3274, HRH2 and IDBG-647824 and ENSBTAG00000044071 and 101909853, Hrh2 and IDBG-153383 and ENSMUSG00000034987 and 15466, Plasma membranes, coupled to cyclic nucleotide second messenger and biological process this GO :0007613 and memory and biological process this GO :0008542 and visual learning and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048565 and digestive tract development and biological process this GO :0048732 and gland development and biological process, histamine receptor activity, this GO :0001696 and gastric acid secretion and biological process this GO :0001697 and histamine-induced gastric acid secretion and biological process this GO :0001698 and gastrin-induced gastric acid secretion and biological process this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004969 and histamine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004969 : histamine receptor activity, this GO :0004969 : histamine receptor activity, 521257, histamine receptor H2 |
| Identity: |
5183 |
| Gene: |
HRH2 |
More about : HRH2 |
| Long gene name: |
histamine receptor H2 |
| Locus: |
5q35, 2 |
| Discovery year: |
1994-12-12 |
| Entrez gene record: |
3274 |
| Pubmed identfication: |
1714721 |
| Classification: |
Histamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000130660 |