| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HRH2 |
| Specificity: |
This antibody reacts specifically with HRH2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HRH2 |
| Gene ID: |
3274 |
| Swiss Prot: |
P25021 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also appears to regulate gastrointestinal motility and intestinal secretion, Possible role in regulating cell growth and differentiation, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity), through a separate G protein-dependent mechanism, The H2 subclass of histamine receptors mediates gastric acid secretion |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
HRH2 Polyclonal Antibody |
| Other name: |
Anti-HRH2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HRH2 |
| Short name: |
Anti-HRH2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-histamine receptor H2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
H2R, HRH2 and IDBG-58464 and ENSG00000113749 and 3274, HRH2 and IDBG-647824 and ENSBTAG00000044071 and 101909853, Hrh2 and IDBG-153383 and ENSMUSG00000034987 and 15466, Plasma membranes, coupled to cyclic nucleotide second messenger and biological process this GO :0007613 and memory and biological process this GO :0008542 and visual learning and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048565 and digestive tract development and biological process this GO :0048732 and gland development and biological process, histamine receptor activity, this GO :0001696 and gastric acid secretion and biological process this GO :0001697 and histamine-induced gastric acid secretion and biological process this GO :0001698 and gastrin-induced gastric acid secretion and biological process this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004969 and histamine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004969 : histamine receptor activity, this GO :0004969 : histamine receptor activity, 521257, histamine receptor H2 |
| Identity: |
5183 |
| Gene: |
HRH2 |
More about : HRH2 |
| Long gene name: |
histamine receptor H2 |
| Locus: |
5q35, 2 |
| Discovery year: |
1994-12-12 |
| Entrez gene record: |
3274 |
| Pubmed identfication: |
1714721 |
| Classification: |
Histamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000130660 |