| Long name: |
Cy5, 5 Conjugated, ALOX12/12 Lipoxygenase Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ALOX12/12 Lipoxygenase |
| Specificity: |
This is a highly specific antibody against ALOX12/12 Lipoxygenase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human 12 Lipoxygenase |
| Gene ID number: |
239 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Murine leukocyte 12 Lipoxygenase is a 75 kDa protein which is 58% homologous to murine platelet 12 Lipoxygenase, Murine leukocyte 12 Lipoxygenase oxidizes arachidonic acid to 12(S)-HpETE and 15(S)-HpETE in a ratio of 3:1, and 70% homologous to porcine leukocyte 12 Lipoxygenase, 12 Lipoxygenase is a non heme iron containing dioxygenase which stereospecifically incorporates molecular oxygen into cis, 4-pentadiene containing polyunsaturated fatty acids, cis-1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
12S-LOX |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
ALOX12/12 Lipoxygenase Conjugated |
| Short name: |
Conjugated, ALOX12/12 Lipoxygenase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, arachidonate 12-lipoxygenase/12 Lipoxygenase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
12-LOX and 12S-LOX and LOG12, ALOX12 and IDBG-22829 and ENSG00000108839 and 239, Alox12 and IDBG-194005 and ENSMUSG00000000320 and 11684, BT, Plasma membranes, acting on single donors with incorporation of molecular oxygen, acting on single donors with incorporation of molecular oxygen, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, incorporation of two atoms of oxygen and also this GO :0046872 : metal ion binding and also this GO :0047977 : hepoxilin-epoxide hydrolase activity and also this GO :0051120 : hepoxilin A3 synthase activity, incorporation of two atoms of oxygen and molecular function this GO :0019369 and arachidonic acid metabolic process and biological process this GO :0019372 and lipoxygenase pathway and biological process this GO :0019395 and fatty acid oxidation and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0042383 and sarcolemma and cellular component this GO :0042554 and superoxide anion generation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043651 and linoleic acid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045603 and positive regulation of endothelial cell differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0047977 and hepoxilin-epoxide hydrolase activity and molecular function this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051120 and hepoxilin A3 synthase activity and molecular function this GO :0051121 and hepoxilin metabolic process and biological process this GO :0051122 and hepoxilin biosynthetic process and biological process this GO :0051901 and positive regulation of mitochondrial depolarization and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0061436 and establishment of skin barrier and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071396 and cellular response to lipid and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process this GO :0090331 and negative regulation of platelet aggregation and biological process this GO :1901751 and leukotriene A4 metabolic process and biological process this GO :2001300 and lipoxin metabolic process and biological process this GO :2001303 and lipoxin A4 biosynthetic process and biological process this GO :2001306 and lipoxin B4 biosynthetic process and biological process, oxidoreductase activity, this GO :0004052 and arachidonate 12-lipoxygenase activity and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006928 and cellular component movement and biological process this GO :0007568 and aging and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010656 and negative regulation of muscle cell apoptotic process and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0016020 and membrane and cellular component this GO :0016165 and lipoxygenase activity and molecular function this GO :0016702 and oxidoreductase activity, this GO :0004052 : arachidonate 12-lipoxygenase activity, this GO :0004052 : arachidonate 12-lipoxygenase activity and also this GO :0005506 : iron ion binding and also this GO :0005515 : protein binding and also this GO :0016165 : lipoxygenase activity and also this GO :0016702 : oxidoreductase activity, this GO :0005506 : iron ion binding, this GO :0005515 : protein binding, this GO :0016165 : lipoxygenase activity, this GO :0016702 : oxidoreductase activity, this GO :0046872 : metal ion binding, this GO :0047977 : hepoxilin-epoxide hydrolase activity, this GO :0051120 : hepoxilin A3 synthase activity, 92152 and IDBG-634488 and ENSBTAG00000021933 and 407169, arachidonate 12-lipoxygenase |
| Identity: |
429 |
| Gene: |
ALOX12 |
More about : ALOX12 |
| Long gene name: |
12S type , arachidonate 12-lipoxygenase |
| Synonyms gene name: |
arachidonate 12-lipoxygenase |
| Synonyms name: |
12S-type , platelet 12-LOX Arachidonate 12-lipoxygenase |
| Locus: |
17p13, 1 |
| Discovery year: |
1991-08-07 |
| GenBank acession: |
M35418 |
| Entrez gene record: |
239 |
| Pubmed identfication: |
1570320 |
| Classification: |
Arachidonate lipoxygenases |
| Havana BLAST/BLAT: |
OTTHUMG00000102088 |