| Long name: |
Girdin (Ser1417) Primary Polyclonal Antibody |
| Also known as: |
Girdin (Ser1417) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Girdin Ser1417 |
| Specificity: |
This is a highly specific antibody against Girdin Ser1417 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser1417 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Girdin around the phosphorylation site of Ser1417 |
| Gene ID number: |
55704 |
| Swiss Prot: |
Q3V6T2 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, Essential for the integrity of the actin cytoskeleton and for cell migration, May be involved in membrane sorting in the early endosome, Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, Required for formation of actin stress fibers and lamellipodia, and regulates DNA replication and cell proliferation (By similarity), but does not possess kinase activity itself, dendritic development and synapse formation, including correct neuron positioning, Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Akt phosphorylation enhancer, CCDC88A, Coiled-coil domain-containing protein 88A, G alpha-interacting vesicle-associated protein, GIRDIN, GIV, GRDN, Girders of actin filament, HkRP1, Hook-related protein 1, KIAA1212, APE |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Girdin (Ser1417) |
| Short name: |
Girdin (Ser1417) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Girdin (Ser1417) (Antibody to) |
| Alternative technique: |
antibodies |