| Long name: |
ALEXA FLUOR 350 Conjugated, Girdin (Ser1417) Polyclonal Antibody |
| Also known as: |
Anti-Girdin Ser1417 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Girdin Ser1417 |
| Specificity: |
This is a highly specific antibody against Girdin Ser1417 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser1417 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Girdin around the phosphorylation site of Ser1417 |
| Gene ID Number: |
55704 |
| Swiss Prot: |
Q3V6T2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, Essential for the integrity of the actin cytoskeleton and for cell migration, May be involved in membrane sorting in the early endosome, Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, Required for formation of actin stress fibers and lamellipodia, and regulates DNA replication and cell proliferation (By similarity), but does not possess kinase activity itself, dendritic development and synapse formation, including correct neuron positioning, Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
Akt phosphorylation enhancer, CCDC88A, Coiled-coil domain-containing protein 88A, G alpha-interacting vesicle-associated protein, GIRDIN, GIV, GRDN, Girders of actin filament, HkRP1, Hook-related protein 1, KIAA1212, APE |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Girdin (Ser1417) |
| Short name: |
Girdin (Ser1417) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Girdin (Ser1417) (Antibody to) |
| Alternative technique: |
antibodies |