| Long name: |
FITC Conjugated, PRLR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PRLR |
| Specificity: |
This is a highly specific antibody against PRLR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
270-305/622 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human Prolactin Receptor |
| Gene ID number: |
5618 |
| Swiss Prot: |
P16471 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT, Isoform 4 is unable to transduce prolactin signaling, Isoform 6 is unable to transduce prolactin signaling, This is a receptor for the anterior pituitary hormone prolactin (PRL) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PRLR Conjugated |
| Short name: |
FITC Conjugated, PRLR Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, prolactin receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, HPRL and hPRLrI and MFAB, PRLR and IDBG-15793 and ENSG00000113494 and 5618, PRLR and IDBG-630451 and ENSBTAG00000025035 and 281422, Prlr and IDBG-129218 and ENSMUSG00000005268 and 19116, metal ion binding, this GO :0004896 and cytokine receptor activity and molecular function this GO :0004925 and prolactin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006694 and steroid biosynthetic process and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0007566 and embryo implantation and biological process this GO :0007595 and lactation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0031904 and endosome lumen and cellular component this GO :0038161 and prolactin signaling pathway and biological process this GO :0042110 and T cell activation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042977 and activation of JAK2 kinase activity and biological process this GO :0042978 and ornithine decarboxylase activator activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0060736 and prostate gland growth and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0061180 and mammary gland epithelium development and biological process, this GO :0004896 : cytokine receptor activity, this GO :0004896 : cytokine receptor activity and also this GO :0004925 : prolactin receptor activity and also this GO :0005515 : protein binding and also this GO :0017046 : peptide hormone binding and also this GO :0042803 : protein homodimerization activity and also this GO :0042978 : ornithine decarboxylase activator activity and also this GO :0046872 : metal ion binding, this GO :0004925 : prolactin receptor activity, this GO :0005515 : protein binding, this GO :0017046 : peptide hormone binding, this GO :0042803 : protein homodimerization activity, this GO :0042978 : ornithine decarboxylase activator activity, this GO :0046872 : metal ion binding, prolactin receptor |
| Identity: |
9446 |
| Gene: |
PRLR |
More about : PRLR |
| Long gene name: |
prolactin receptor |
| Locus: |
5p13, 2 |
| Discovery year: |
1989-12-01 |
| Entrez gene record: |
5618 |
| Havana BLAST/BLAT: |
OTTHUMG00000090789 |