| Long name: |
HRP Conjugated, KIRREL1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KIRREL1 |
| Specificity: |
This is a highly specific antibody against KIRREL1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human KIRREL1/NEPH1 |
| Gene ID number: |
55243 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Neph1 consists of a signal peptide, Neph1 interacts with nephrin in vitro and in vivo, Neph1 is abundantly expressed in the kidney, Neph1 is crucial for the integrity of the slit diaphragm, Specifically expressed in podocytes of kidney glomeruli, a transmembrane domain and a cytoplasmic tail, an RGD sequence, and able to stimulate transcriptional activation in a model system, and early postnatal death, and plays a significant role in the normal development and function of the glomerular permeability, as Neph1 gene knockout mice results in effacement of glomerular podocytes, five Ig-like C2-type domains with the middle domain overlapping with a PKD-like domain, heavy proteinuria, specifically expressed in podocytes of kidney glomeruli, such as the activation the transcription factor AP-1 via the stimulation of a MAPK module, Neph1(Kirrel) belongs to a family of three closely related transmembrane proteins of the Ig superfamily with a structure similar to that of nephrin, Tissue specificity:Abundantly expressed in kidney |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIRR1_HUMAN, KIRR1_HUMAN, Kin of IRRE like, Kin of IRRE like protein 1, Kin of IRRE-like protein 1, Kin of irregular chiasm like protein 1, Kin of irregular chiasm-like protein 1, Kirrel, MGC129542, MGC129543, NEPH 1, NEPH1, Nephrin like protein 1, Nephrin related, Nephrin-like protein 1, Kin of IRRE like Drosophila |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
KIRREL1 Conjugated |
| Short name: |
Conjugated, KIRREL1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, KIRREL1 (Antibody to) |
| Alternative technique: |
antibodies |