| Long name: |
FITC Conjugated, KIRREL1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KIRREL1 |
| Specificity: |
This is a highly specific antibody against KIRREL1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human KIRREL1/NEPH1 |
| Gene ID number: |
55243 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Neph1 consists of a signal peptide, Neph1 interacts with nephrin in vitro and in vivo, Neph1 is abundantly expressed in the kidney, Neph1 is crucial for the integrity of the slit diaphragm, Specifically expressed in podocytes of kidney glomeruli, a transmembrane domain and a cytoplasmic tail, an RGD sequence, and able to stimulate transcriptional activation in a model system, and early postnatal death, and plays a significant role in the normal development and function of the glomerular permeability, as Neph1 gene knockout mice results in effacement of glomerular podocytes, five Ig-like C2-type domains with the middle domain overlapping with a PKD-like domain, heavy proteinuria, specifically expressed in podocytes of kidney glomeruli, such as the activation the transcription factor AP-1 via the stimulation of a MAPK module, Neph1(Kirrel) belongs to a family of three closely related transmembrane proteins of the Ig superfamily with a structure similar to that of nephrin, Tissue specificity:Abundantly expressed in kidney |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
KIRR1_HUMAN, KIRR1_HUMAN, Kin of IRRE like, Kin of IRRE like protein 1, Kin of IRRE-like protein 1, Kin of irregular chiasm like protein 1, Kin of irregular chiasm-like protein 1, Kirrel, MGC129542, MGC129543, NEPH 1, NEPH1, Nephrin like protein 1, Nephrin related, Nephrin-like protein 1, Kin of IRRE like Drosophila |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KIRREL1 Conjugated |
| Short name: |
FITC Conjugated, KIRREL1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, KIRREL1 (Antibody to) |
| Alternative technique: |
antibodies |