| Long name: |
MRC2 Primary Polyclonal Antibody |
| Also known as: |
MRC2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MRC2 |
| Specificity: |
This is a highly specific antibody against MRC2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-420/1479 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MRC2/CD280 |
| Gene ID number: |
9902 |
| Swiss Prot: |
Q9UBG0 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis, May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, May contribute to cellular uptake, May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs), May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover, and thus may regulate protease activity at the cell surface, remodeling and degradation of extracellular collagen matrices, May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C-type lectin domain family 13 member E, C-type mannose receptor 2, CLEC13E, ENDO180, Endocytic receptor 180, KIAA0709, MRC2, Macrophage mannose receptor 2, UPAR-associated protein, UPARAP, Urokinase receptor-associated protein, Urokinase-type plasminogen activator receptor-associated protein, CD280 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MRC2 |
| Short name: |
MRC2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
C type 2 (Antibody to), mannose receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C type 2, CD280 and CLEC13E and ENDO180 and UPARAP, MRC2 and IDBG-63031 and ENSG00000011028 and 9902, MRC2 and IDBG-641433 and ENSBTAG00000015739 and 529049, Mrc2 and IDBG-213230 and ENSMUSG00000020695 and 17534, Plasma membranes, carbohydrate binding, this GO :0001649 and osteoblast differentiation and biological process this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0006897 and endocytosis and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0030574 and collagen catabolic process and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0030246 : carbohydrate binding, this GO :0005518 : collagen binding, this GO :0030246 : carbohydrate binding, mannose receptor |
| Identity: |
16875 |
| Gene: |
MRC2 |
More about : MRC2 |
| Long gene name: |
mannose receptor C type 2 |
| Synonyms gene name: |
C type 2 , mannose receptor |
| Synonyms: |
KIAA0709 ENDO180 CLEC13E CD280 |
| Synonyms name: |
C-type lectin domain family 13 member E endocytic receptor 180 |
| Locus: |
17q23 |
| Discovery year: |
2002-09-24 |
| GenBank acession: |
AB014609 |
| Entrez gene record: |
9902 |
| Pubmed identfication: |
9734811 8702911 |
| Classification: |
CD molecules C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000179178 |