| Long name: |
ALEXA FLUOR 594 Conjugated, MAPK8IP1 Polyclonal Antibody |
| Also known as: |
Anti-MAPK8IP1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MAPK8IP1 |
| Specificity: |
This is a highly specific antibody against MAPK8IP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
435-485/711 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JIP1/MAPK8IP1 |
| Gene ID Number: |
9479 |
| Swiss Prot: |
Q9UQF2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Appears to have a role in cell signaling in mature and developing nerve terminals, Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun, Directly, Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response, May also participate in ApoER2-specific reelin signaling, May function as a regulator of vesicle transport, Required for JNK activation in response to excitotoxic stress, or indirectly, regulates GLUT2 gene expression and beta-cell function, through interactions with the JNK-signaling components and motor proteins (By similarity), The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
IB1 JIP-1 JIP1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
MAPK8IP1 |
| Short name: |
MAPK8IP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, mitogen-activated protein phosphorylation catalyst 8 interacting protein 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0007165 and signal transduction and biological process this GO :0007258 and JUN phosphorylation and biological process this GO :0008432 and JUN kinase binding and molecular function this GO :0009967 and positive regulation of signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0016192 and vesicle-mediated transport and biological process this GO :0019894 and kinesin binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031434 and mitogen-activated protein kinase kinase binding and molecular function this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0044294 and dendritic growth cone and cellular component this GO :0044295 and axonal growth cone and cellular component this GO :0044297 and cell body and cellular component this GO :0044302 and dentate gyrus mossy fiber and cellular component this GO :0045202 and synapse and cellular component this GO :0046328 and regulation of JNK cascade and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, IB1 and JIP-1 and JIP1 and PRKM8IP, MAPK8IP1 and IDBG-41200 and ENSG00000121653 and 9479, Mapk8ip1 and IDBG-192264 and ENSMUSG00000027223 and 19099, identical protein binding, nuclei, this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005078 and MAP-kinase scaffold activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0004860 : protein kinase inhibitor activity, this GO :0004860 : protein kinase inhibitor activity and also this GO :0005078 : MAP-kinase scaffold activity and also this GO :0005515 : protein binding and also this GO :0008432 : JUN kinase binding and also this GO :0019894 : kinesin binding and also this GO :0019901 : protein kinase binding and also this GO :0031434 : mitogen-activated protein kinase kinase binding and also this GO :0031435 : mitogen-activated protein kinase kinase kinase binding and also this GO :0042802 : identical protein binding, this GO :0005078 : MAP-kinase scaffold activity, this GO :0005515 : protein binding, this GO :0008432 : JUN kinase binding, this GO :0019894 : kinesin binding, this GO :0019901 : protein kinase binding, this GO :0031434 : mitogen-activated protein kinase kinase binding, this GO :0031435 : mitogen-activated protein kinase kinase kinase binding, this GO :0042802 : identical protein binding, 105291 and IDBG-637017 and ENSBTAG00000000317 and 524806, mitogen-activated protein kinase 8 interacting protein 1 |
| Identity: |
6882 |
| Gene: |
MAPK8IP1 |
More about : MAPK8IP1 |
| Long gene name: |
mitogen-activated protein kinase 8 interacting protein 1 |
| Synonyms gene: |
PRKM8IP |
| Locus: |
11p11, 2 |
| Discovery year: |
1999-06-11 |
| Entrez gene record: |
9479 |
| Pubmed identfication: |
9235893 9442013 |
| RefSeq identity: |
NM_005456 |
| Havana BLAST/BLAT: |
OTTHUMG00000134324 |