| Long name: |
ROR beta Primary Polyclonal Antibody |
| Also known as: |
ROR beta PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ROR beta |
| Specificity: |
This is a highly specific antibody against ROR beta |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
390-440/470 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RORB |
| Gene ID number: |
6096 |
| Swiss Prot: |
Q92753 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Considered to have intrinsic transcriptional activity, In cone photoreceptor cells, Involved in the regulation of the period length and stability of the circadian rhythm, May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons, May control cytoarchitectural patterning of neocortical neurons during development, May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity), Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway, Required for normal postnatal development of rod and cone photoreceptor cells, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity, regulates transcription of OPN1SW, Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Nuclear receptor ROR-beta, Nuclear receptor RZR beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, RAR related orphan receptor B, RAR related orphan receptor beta, ROR BETA, RORB_HUMAN, RZR BETA, RZRB, Retinoic acid binding receptor beta, Retinoid-related orphan receptor-beta, Rorb, NR1F2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ROR beta |
| Short name: |
ROR beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ROR b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
43773 |
| Gene: |
LINC-ROR |
More about : LINC-ROR |
| Long gene name: |
long intergenic non-protein coding RNA, regulator of reprogramming |
| Synonyms: |
lincRNA-RoR lincRNA-ST8SIA3 ROR |
| Locus: |
18q21, 31 |
| Discovery year: |
2012-05-01 |
| GenBank acession: |
HQ315778 |
| Entrez gene record: |
100885779 |
| Pubmed identfication: |
21057500 23208419 23541921 23597480 24463816 |
| RefSeq identity: |
NR_048536 |
| Classification: |
Long non-coding RNAs Competing endogenous long non-coding RNAs |
| Havana BLAST/BLAT: |
OTTHUMG00000171587 |