| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ROR beta |
| Specificity: |
This antibody reacts specifically with ROR beta |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RORB |
| Gene ID: |
6096 |
| Swiss Prot: |
Q92753 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Considered to have intrinsic transcriptional activity, In cone photoreceptor cells, Involved in the regulation of the period length and stability of the circadian rhythm, May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons, May control cytoarchitectural patterning of neocortical neurons during development, May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity), Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway, Required for normal postnatal development of rod and cone photoreceptor cells, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity, regulates transcription of OPN1SW, Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
lincRNA-RoR lincRNA-ST8SIA3 ROR |
| Also known as: |
ROR beta Polyclonal Antibody |
| Other name: |
Anti-ROR beta Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ROR beta |
| Short name: |
Anti-ROR beta (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ROR b (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
43773 |
| Gene: |
LINC-ROR |
More about : LINC-ROR |
| Long gene name: |
long intergenic non-protein coding RNA, regulator of reprogramming |
| Locus: |
18q21, 31 |
| Discovery year: |
2012-05-01 |
| GenBank acession: |
HQ315778 |
| Entrez gene record: |
100885779 |
| Pubmed identfication: |
21057500 23208419 23541921 23597480 24463816 |
| RefSeq identity: |
NR_048536 |
| Classification: |
Long non-coding RNAs Competing endogenous long non-coding RNAs |
| Havana BLAST/BLAT: |
OTTHUMG00000171587 |