| Long name: |
Cy5, 5 Conjugated, H3-K4-HMTase SETD7 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
H3-K4-HMTase SETD7 |
| Specificity: |
This is a highly specific antibody against H3-K4-HMTase SETD7 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Histone H4 K4 methyltransferase SETD7 |
| Gene ID number: |
80854 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also able to demethylated 'Lys-372' of p53/TP53 in vitro, H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, Has also methyltransferase activity toward non-histone proteins such as p53/TP53, Monomethylates 'Lys-189' of TAF10, Monomethylates 'Lys-372' of p53/TP53, Plays a central role in the transcriptional activation of genes such as collagenase or insulin, Recruited by IPF1/PDX-1 to the insulin promoter, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins, leading to activate transcription, leading to increase the affinity of TAF10 for RNA polymerase II, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation, Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
KIAA1717 SET7 SET7/9 Set9 KMT7 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
H3-K4-HMTase SETD7 Conjugated |
| Short name: |
Conjugated, H3-K4-HMTase SETD7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, H3-K4-HMTase SETD7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30412 |
| Gene: |
SETD7 |
More about : SETD7 |
| Long gene name: |
SET domain containing lysine methyltransferase 7 |
| Locus: |
4q31, 1 |
| Discovery year: |
2006-02-15 |
| GenBank acession: |
AB051504 |
| Entrez gene record: |
80854 |
| Pubmed identfication: |
11850410 11779497 |
| RefSeq identity: |
NM_030648 |
| Classification: |
Lysine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000133385 |