| Long name: |
Biotin Conjugated, H3-K4-HMTase SETD7 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
H3-K4-HMTase SETD7 |
| Specificity: |
This is a highly specific antibody against H3-K4-HMTase SETD7 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Histone H4 K4 methyltransferase SETD7 |
| Gene ID number: |
80854 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also able to demethylated 'Lys-372' of p53/TP53 in vitro, H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, Has also methyltransferase activity toward non-histone proteins such as p53/TP53, Monomethylates 'Lys-189' of TAF10, Monomethylates 'Lys-372' of p53/TP53, Plays a central role in the transcriptional activation of genes such as collagenase or insulin, Recruited by IPF1/PDX-1 to the insulin promoter, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins, leading to activate transcription, leading to increase the affinity of TAF10 for RNA polymerase II, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation, Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIAA1717 SET7 SET7/9 Set9 KMT7 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
H3-K4-HMTase SETD7 Conjugated |
| Short name: |
Conjugated, H3-K4-HMTase SETD7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, H3-K4-HMTase SETD7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30412 |
| Gene: |
SETD7 |
More about : SETD7 |
| Long gene name: |
SET domain containing lysine methyltransferase 7 |
| Locus: |
4q31, 1 |
| Discovery year: |
2006-02-15 |
| GenBank acession: |
AB051504 |
| Entrez gene record: |
80854 |
| Pubmed identfication: |
11850410 11779497 |
| RefSeq identity: |
NM_030648 |
| Classification: |
Lysine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000133385 |