| Long name: |
ALEXA FLUOR 594 Conjugated, SLC5A8 Polyclonal Antibody |
| Also known as: |
Anti-SLC5A8 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLC5A8 |
| Specificity: |
This is a highly specific antibody against SLC5A8 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
301-336/610 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC5A8 |
| Gene ID Number: |
160728 |
| Swiss Prot: |
Q8N695 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a tumor suppressor, Catalyzes passive carrier mediated diffusion of iodide, D-lactate, May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract, May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons, Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane, acetate, acetoacetate and alpha-ketoisocaproate), benzoate, including transport of monocarboxylates (short-chain fatty acids including L-lactate, lactate, mocarboxylate drugs (nicotinate, propionate, prostate cancer and glioma cell lines, pyruvate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, suppressing colony formation in colon cancer, valerate and butyrate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1, Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AIT |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
SLC5A8 |
| Short name: |
SLC5A8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, member 8 (Antibody to), solute carrier family 5 (iodide transporter) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, SLC5A8 and IDBG-547244 and ENSG00000256870 and 160728, SMCT1 and IDBG-636931 and ENSBTAG00000011525 and 615734, Slc5a8 and IDBG-183999 and ENSMUSG00000020062 and 216225, member 8, symporter activity, this GO :0005215 and transporter activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0006811 and ion transport and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0015293 and symporter activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005215 : transporter activity, this GO :0005215 : transporter activity and also this GO :0015293 : symporter activity, this GO :0015293 : symporter activity, solute carrier family 5 (iodide transporter) |
| Identity: |
19119 |
| Gene: |
SLC5A8 |
More about : SLC5A8 |
| Long gene name: |
solute carrier family 5 member 8 |
| Synonyms gene name: |
member 8 , member 8 solute carrier family 5 (sodium/monocarboxylate cotransporter), solute carrier family 5 (iodide transporter) |
| Locus: |
12q23, 1-q23, 2 |
| Discovery year: |
2003-05-12 |
| GenBank acession: |
AY081220 |
| Entrez gene record: |
160728 |
| Pubmed identfication: |
12107270 12829793 |
| RefSeq identity: |
NM_145913 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000170499 |