| Catalog number: | bs-6058R-A488 |
|---|---|
| Price: | 263 € |
| Supplier: | Bioss Primary Unconjugated Antibodies |
| Product name: | Nicastrin Antibody, ALEXA FLUOR 488 |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, Nicastrin Polyclonal Antibody |
|---|---|
| Also known as: | Anti-Nicastrin PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Nicastrin |
| Specificity: | This is a highly specific antibody against Nicastrin |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 33-83/709 |
| Subcellular location: | Extracellular |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nicastrin |
| Gene ID Number: | 23385 |
| Swiss Prot: | Q92542 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein), Essential subunit of the gamma-secretase complex |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Synonyms: | KIAA0253 APH2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Nicastrin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | Nicastrin |
| Short name: | Nicastrin Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, Nicastrin (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 17091 |
| Gene: | NCSTN | More about : NCSTN |
| Long gene name: | nicastrin |
| Locus: | 1q23, 2 |
| Discovery year: | 2005-02-08 |
| GenBank acession: | AF240468 |
| Entrez gene record: | 23385 |
| Pubmed identfication: | 9039502 10993067 |
| RefSeq identity: | NM_015331 |
| Havana BLAST/BLAT: | OTTHUMG00000033110 |
| Locus Specific Databases: | LRG_223 |
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