| Long name: |
ALEXA FLUOR 647 Conjugated, Nicastrin Polyclonal Antibody |
| Also known as: |
Anti-Nicastrin PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Nicastrin |
| Specificity: |
This is a highly specific antibody against Nicastrin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
33-83/709 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nicastrin |
| Gene ID Number: |
23385 |
| Swiss Prot: |
Q92542 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein), Essential subunit of the gamma-secretase complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
KIAA0253 APH2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Nicastrin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Nicastrin |
| Short name: |
Nicastrin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Nicastrin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17091 |
| Gene: |
NCSTN |
More about : NCSTN |
| Long gene name: |
nicastrin |
| Locus: |
1q23, 2 |
| Discovery year: |
2005-02-08 |
| GenBank acession: |
AF240468 |
| Entrez gene record: |
23385 |
| Pubmed identfication: |
9039502 10993067 |
| RefSeq identity: |
NM_015331 |
| Havana BLAST/BLAT: |
OTTHUMG00000033110 |
| Locus Specific Databases: |
LRG_223 |