| Long name: |
partial, Recombinant Human Niemann-Pick C1 protein (NPC1) |
| Alternative names: |
Niemann-Pick C1 protein, Niemann-Pick C1 protein, Niemann-Pick disease, type C1, Niemann-Pick C1 protein |
| Other gene names: |
NPC, NPC1, NPC1 |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, partial is a recombinant protein expressed in Yeast , Niemann-Pick C1 protein (NPC1) |
| Product category: |
Recombinant Proteins |
| Expression system: |
Yeast |
| Available also expressed in:: |
Yeast, E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
We can custom produce according to your specifications, This item requires custom production and lead time is between 5-9 weeks |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Niemann-Pick C1 protein (NPC1) partial |
| Short name: |
Niemann-Pick C1 protein (NPC1) partial |
| Species: |
Humans, Human |
| Alternative name: |
classification C1), partial, sapiens Niemann-Pick C1 protein (Niemann-Pick disease, H |
| Alternative to gene target: |
NPC, NPC1 and IDBG-1600 and ENSG00000141458 and 4864, NPC1 and IDBG-643938 and ENSBTAG00000015195 and 286772, Npc1 and IDBG-128877 and ENSMUSG00000024413 and 18145, cholesterol binding, nuclei, this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005764 and lysosome and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006486 and protein glycosylation and biological process this GO :0006897 and endocytosis and biological process this GO :0006914 and autophagy and biological process this GO :0007041 and lysosomal transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007628 and adult walking behavior and biological process this GO :0008158 and hedgehog receptor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008206 and bile acid metabolic process and biological process this GO :0015248 and sterol transporter activity and molecular function this GO :0015485 and cholesterol binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016242 and negative regulation of macroautophagy and biological process this GO :0030301 and cholesterol transport and biological process this GO :0031579 and membrane raft organization and biological process this GO :0031902 and late endosome membrane and cellular component this GO :0031982 and vesicle and cellular component this GO :0033344 and cholesterol efflux and biological process this GO :0042493 and response to drug and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0045121 and membrane raft and cellular component this GO :0046686 and response to cadmium ion and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0060548 and negative regulation of cell death and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071383 and cellular response to steroid hormone stimulus and biological process this GO :0071404 and cellular response to low-density lipoprotein particle stimulus and biological process this GO :0090150 and establishment of protein localization to membrane and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0008158 : hedgehog receptor activity and also this GO :0015248 : sterol transporter activity and also this GO :0015485 : cholesterol binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0008158 : hedgehog receptor activity, this GO :0015248 : sterol transporter activity, this GO :0015485 : cholesterol binding, type C1, Niemann-Pick disease |
| Identity: |
7897 |
| Gene: |
NPC1 |
More about : NPC1 |
| Long gene name: |
NPC intracellular cholesterol transporter 1 |
| Synonyms gene name: |
Niemann-Pick disease, type C1 |
| Locus: |
18q11, 2 |
| Discovery year: |
1993-04-13 |
| GenBank acession: |
AF002020 |
| Entrez gene record: |
4864 |
| Pubmed identfication: |
8446622 |
| RefSeq identity: |
NM_000271 |
| Havana BLAST/BLAT: |
OTTHUMG00000131873 |