| Long name: |
ALEXA FLUOR 488 Conjugated, PCDHB11 Polyclonal Antibody |
| Also known as: |
Anti-PCDHB11 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PCDHB11 |
| Specificity: |
This is a highly specific antibody against PCDHB11 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PCDHB11 |
| Gene ID Number: |
56125 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters, The beta cluster contains 16 genes and 3 pseudogenes, The extracellular domains interact in a homophilic manner to specify differential cell-cell connections, Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections, These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins, Unlike the alpha and gamma clusters, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily, not sharing common 3' exons as expected, one of three related gene clusters tandemly linked on chromosome five, the transcripts from these genes are made up of only one large exon, PCDHB11 is a member of the protocadherin beta gene cluster |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PCDH-BETA11 ME2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PCDHB11 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PCDHB11 |
| Short name: |
PCDHB11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, protocadherin b 11 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PCDHB11 and IDBG-50113 and ENSG00000197479 and 56125, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007399 and nervous system development and biological process this GO :0007416 and synapse assembly and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016339 and calcium-dependent cell-cell adhesion and biological process, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding, protocadherin beta 11 |
| Identity: |
8682 |
| Gene: |
PCDHB11 |
More about : PCDHB11 |
| Long gene name: |
protocadherin beta 11 |
| Synonyms name: |
cadherin ME2 |
| Locus: |
5q31, 3 |
| Discovery year: |
2000-06-28 |
| GenBank acession: |
AF152490 |
| Entrez gene record: |
56125 |
| Pubmed identfication: |
10380929 |
| RefSeq identity: |
NM_018931 |
| Classification: |
Clustered protocadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000129618 |