| Long name: |
Recombinant Human Toll-like receptor 2 (TLR2) |
| Alternative names: |
CD_antigen: CD282, Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2, toll-like receptor 2, toll/interleukin 1 receptor-like 4, toll/interleukin-1 receptor-like protein 4, toll-like receptor 2 |
| Gene name: |
TLR2 |
| Other gene names: |
CD282, TIL4, TIL4, TLR2, TLR2 |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, coli, Toll-like receptor 2 (TLR2) is a recombinant protein expressed in E |
| Product category: |
Recombinant Proteins |
| Expression system: |
coli, E |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE)(SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, Notes: Repeated freezing and thawing is not recommended, Store working aliquots at 4 degree C for up to one week, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Toll-like receptor 2 (TLR2) |
| Short name: |
Toll-like receptor 2 (TLR2) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Toll-like receptor 2 (toll-like receptor 2), H |
| Alternative to gene target: |
CD282 and TIL4, Cell surfaces, TLR2 and IDBG-41789 and ENSG00000137462 and 7097, TLR2 and IDBG-629032 and ENSBTAG00000008008 and 281534, Tlr2 and IDBG-154818 and ENSMUSG00000027995 and 24088, lipopeptide binding, this GO :0001666 and response to hypoxia and biological process this GO :0001774 and microglial cell activation and biological process this GO :0001875 and lipopolysaccharide receptor activity and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002238 and response to molecule of fungal origin and biological process this GO :0002687 and positive regulation of leukocyte migration and biological process this GO :0002752 and cell surface pattern recognition receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006691 and leukotriene metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008329 and signaling pattern recognition receptor activity and molecular function this GO :0009617 and response to bacterium and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032289 and central nervous system myelin formation and biological process this GO :0032493 and response to bacterial lipoprotein and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032570 and response to progesterone and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032700 and negative regulation of interleukin-17 production and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032741 and positive regulation of interleukin-18 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032868 and response to insulin and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035354 and Toll-like receptor 1-Toll-like receptor 2 protein complex and cellular component this GO :0035355 and Toll-like receptor 2-Toll-like receptor 6 protein complex and cellular component this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042495 and detection of triacyl bacterial lipopeptide and biological process this GO :0042496 and detection of diacyl bacterial lipopeptide and biological process this GO :0042497 and triacyl lipopeptide binding and molecular function this GO :0042498 and diacyl lipopeptide binding and molecular function this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0042892 and chloramphenicol transport and biological process this GO :0042995 and cell projection and cellular component this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0044297 and cell body and cellular component this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048714 and positive regulation of oli this GO dendrocyte differentiation and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0052063 and induction by symbiont of defense-related host nitric oxide production and biological process this GO :0060907 and positive regulation of macrophage cytokine production and biological process this GO :0070542 and response to fatty acid and biological process this GO :0070891 and lipoteichoic acid binding and molecular function this GO :0071221 and cellular response to bacterial lipopeptide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0071224 and cellular response to peptidoglycan and biological process this GO :0071723 and lipopeptide binding and molecular function this GO :0071726 and cellular response to diacyl bacterial lipopeptide and biological process this GO :0071727 and cellular response to triacyl bacterial lipopeptide and biological process, this GO :0001875 : lipopolysaccharide receptor activity, this GO :0001875 : lipopolysaccharide receptor activity and also this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0008329 : signaling pattern recognition receptor activity and also this GO :0042497 : triacyl lipopeptide binding and also this GO :0042498 : diacyl lipopeptide binding and also this GO :0042834 : peptidoglycan binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0070891 : lipoteichoic acid binding and also this GO :0071723 : lipopeptide binding, this GO :0004872 : receptor activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0008329 : signaling pattern recognition receptor activity, this GO :0042497 : triacyl lipopeptide binding, this GO :0042498 : diacyl lipopeptide binding, this GO :0042834 : peptidoglycan binding, this GO :0046982 : protein heterodimerization activity, this GO :0070891 : lipoteichoic acid binding, this GO :0071723 : lipopeptide binding, toll-like receptor 2 |
| Identity: |
11848 |
| Gene: |
TLR2 |
More about : TLR2 |
| Long gene name: |
toll like receptor 2 |
| Synonyms gene name: |
toll-like receptor 2 |
| Synonyms: |
TIL4 CD282 |
| Locus: |
4q31, 3 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88878 |
| Entrez gene record: |
7097 |
| Pubmed identfication: |
9435236 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000161525 |