RIPK-1 Antibody, Cy7 Conjugated

Catalog number:	bs-5805R-Cy7 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	RIPK-1 Antibody, Cy7 Conjugated
Quantity:	0.1ml
Related search:	antibody antibodies rip kinase death deg

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Long name:	Cy7 Conjugated, RIPK-1 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy7
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	RIPK-1
Specificity:	This is a highly specific antibody against RIPK-1
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	600-650/671
Subcellular location:	Cell membrane, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human RIPK-1/RIP
Gene ID number:	8737
Swiss Prot:	Q13546
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death, Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, Polyubiquitinated protein binds to IKBKG/NEMO, RIPK1 and RIPK3 association, TRADD and TRAF2 are recruited to the receptor, Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, Upon activation of TNFR1 by the TNF-alpha family cytokines, a critical event for NF-kappa-B activation, activation of pathogen recognition receptors (PRRs), and DNA damage, and thereby activates the MAP3K5-JNK apoptotic cascade, forms a necrosis-inducing complex, in particular, the regulatory subunit of the IKK complex, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules, Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	743nm/767nm
Synonyms:	Cell death protein RIP, RIP-1, RIP1, RIPK1, Receptor-interacting protein 1, Receptor-interacting serine/threonine-protein kinase 1, Serine/threonine-protein kinase RIP, RIP
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target:	RIPK-1 Conjugated
Short name:	Conjugated, RIPK-1 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy7
Alternative name:	cyanine 7 coupled, RIPK-1 (Antibody to)
Alternative technique:	antibodies

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