| Long name: |
ALEXA FLUOR 594 Conjugated, BNIP3L Polyclonal Antibody |
| Also known as: |
Anti-BNIP3L PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BNIP3L |
| Specificity: |
This is a highly specific antibody against BNIP3L |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
170-219/219 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BNIP3L |
| Gene ID Number: |
665 |
| Swiss Prot: |
O60238 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix, Can overcome the suppressors BCL-2 and BCL-XL, Inhibits apoptosis induced by BNIP3, Interacts with viral and cellular anti-apoptosis proteins, Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, May function as a tumor suppressor, The physical interaction of SPATA18/MIEAP, although high levels of BCL-XL expression will inhibit apoptosis, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria, Induces apoptosis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Nix BNIP3a |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
BNIP3L |
| Short name: |
BNIP3L Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, B-cell CLL/lymphoma 2/adenovirus E1B 19kDa interacting protein 3-like (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BNIP3L and IDBG-13074 and ENSG00000104765 and 665, BNIP3L and IDBG-635626 and ENSBTAG00000021307 and 534615, BNIP3a and NIX, Bnip3l and IDBG-175760 and ENSMUSG00000022051 and 100043324, nuclei, protein heterodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005521 and lamin binding and molecular function this GO :0005635 and nuclear envelope and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005740 and mitochondrial envelope and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031224 and intrinsic component of membrane and cellular component this GO :0035694 and mitochondrial protein catabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051607 and defense response to virus and biological process this GO :0097345 and mitochondrial outer membrane permeabilization and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005521 : lamin binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity, this GO :0005521 : lamin binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, 12177, 102641641, BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| Identity: |
1085 |
| Gene: |
BNIP3L |
More about : BNIP3L |
| Long gene name: |
BCL2 interacting protein 3 like |
| Synonyms gene name: |
BCL2/adenovirus E1B 19kDa interacting protein 3 like |
| Locus: |
8p21, 2 |
| Discovery year: |
1997-07-01 |
| GenBank acession: |
AB004788 |
| Entrez gene record: |
665 |
| Pubmed identfication: |
9523198 9973195 |
| RefSeq identity: |
NM_004331 |
| Havana BLAST/BLAT: |
OTTHUMG00000099433 |