| Long name: |
FITC Conjugated, TUSC2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TUSC2 |
| Specificity: |
This is a highly specific antibody against TUSC2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TUSC2 |
| Gene ID number: |
11334 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AKT, Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions, PDGFR, Restoration of TUSC2 function in 3p21, TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, and c-Kit, c-Abl, 3 region where allele losses and genetic alterations occur early and frequently for many human cancers, 3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics, TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FUS1 PAP C3orf11 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TUSC2 Conjugated |
| Short name: |
FITC Conjugated, TUSC2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TUSC2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17034 |
| Gene: |
TUSC2 |
More about : TUSC2 |
| Long gene name: |
tumor suppressor candidate 2 |
| Synonyms gene: |
PDAP2 |
| Synonyms gene name: |
PDGFA associated protein 2 |
| Locus: |
3p21, 31 |
| Discovery year: |
2003-09-25 |
| GenBank acession: |
AF055479 |
| Entrez gene record: |
11334 |
| Pubmed identfication: |
8780057 11593436 |
| RefSeq identity: |
NM_007275 |
| Havana BLAST/BLAT: |
OTTHUMG00000156877 |