| Long name: |
ALEXA FLUOR 488 Conjugated, RASGRF1 (Ser929) Polyclonal Antibody |
| Also known as: |
Anti-RASGRF1 Ser929 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RASGRF1 Ser929 |
| Specificity: |
This is a highly specific antibody against RASGRF1 Ser929 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser929 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human RasGRF1 around the phosphorylation site of Ser929 |
| Gene ID Number: |
5923 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Alternatively spliced transcript variants encoding distinct isoforms have been reported, Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein, Mar 2009], Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory, The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, [provided by RefSeq, and G protein beta-gamma subunit, muscarinic receptors, The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CDC25L CDC25 GRF55 H-GRF55 GNRP PP13187 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the RASGRF1 (Ser929) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
RASGRF1 (Ser929) |
| Short name: |
RASGRF1 (Ser929) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Ras protein-specific guanine nucleotide-releasing factor 1 (Ser929) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CDC25 and CDC25L and GNRP and GRF1 and GRF55 and H-GRF55 and PP13187 and ras-GRF1, Plasma membranes, RASGRF1 and IDBG-25346 and ENSG00000058335 and 5923, RASGRF1 and IDBG-630181 and ENSBTAG00000019940 and 520039, Rasgrf1 and IDBG-190479 and ENSMUSG00000032356 and 19417, glutamate receptor binding, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005088 and Ras guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007616 and long-term memory and biological process this GO :0008283 and cell proliferation and biological process this GO :0030426 and growth cone and cellular component this GO :0031175 and neuron projection development and biological process this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0032863 and activation of Rac GTPase activity and biological process this GO :0035020 and regulation of Rac protein signal transduction and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035254 and glutamate receptor binding and molecular function this GO :0043005 and neuron projection and cellular component this GO :0046578 and regulation of Ras protein signal transduction and biological process this GO :0046579 and positive regulation of Ras protein signal transduction and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048168 and regulation of neuronal synaptic plasticity and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :2000310 and regulation of N-methyl-D-aspartate selective glutamate receptor activity and biological process, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005088 : Ras guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0035254 : glutamate receptor binding, this GO :0005088 : Ras guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005515 : protein binding, this GO :0035254 : glutamate receptor binding, Ras protein-specific guanine nucleotide-releasing factor 1 |
| Identity: |
9875 |
| Gene: |
RASGRF1 |
More about : RASGRF1 |
| Long gene name: |
Ras protein specific guanine nucleotide releasing factor 1 |
| Synonyms gene: |
GRF1 |
| Locus: |
15q25, 1 |
| Discovery year: |
1994-02-11 |
| GenBank acession: |
M91815 |
| Entrez gene record: |
5923 |
| Pubmed identfication: |
7684828 1379731 |
| RefSeq identity: |
NM_002891 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000144172 |