| Long name: |
FITC Conjugated, VAV1 (Tyr160) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
VAV1 Tyr160 |
| Specificity: |
This is a highly specific antibody against VAV1 Tyr160 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr160 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
150-165/845 |
| Subcellular location: |
Intracellular |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human VAV1 around the phosphorylation site of Tyr160 |
| Gene ID number: |
7409 |
| Swiss Prot: |
P15498 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
thus leading to cell differentiation and/or proliferation, Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VAV1 (Tyr160) Conjugated |
| Short name: |
FITC Conjugated, VAV1 (Tyr160) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, vav 1 guanine nucleotide exchange factor (Tyr160) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, DNA-templated and biological process this GO :0006909 and pha this GO cytosis and biological process this GO :0006955 and immune response and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0030168 and platelet activation and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0030676 and Rac guanyl-nucleotide exchange factor activity and molecular function this GO :0031295 and T cell costimulation and biological process this GO :0032314 and regulation of Rac GTPase activity and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042110 and T cell activation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043087 and regulation of GTPase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process this GO :0097190 and apoptotic signaling pathway and biological process, VAV, VAV1 and IDBG-22055 and ENSG00000141968 and 7409, VAV1 and IDBG-643888 and ENSBTAG00000039160 and, Vav1 and IDBG-194093 and ENSMUSG00000034116 and 22324, metal ion binding, this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006355 and regulation of transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0030676 : Rac guanyl-nucleotide exchange factor activity and also this GO :0046872 : metal ion binding, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005515 : protein binding, this GO :0030676 : Rac guanyl-nucleotide exchange factor activity, this GO :0046872 : metal ion binding, vav 1 guanine nucleotide exchange factor |
| Identity: |
12657 |
| Gene: |
VAV1 |
More about : VAV1 |
| Long gene name: |
vav guanine nucleotide exchange factor 1 |
| Synonyms gene: |
VAV |
| Synonyms gene name: |
vav 1 oncogene vav 1 guanine nucleotide exchange factor |
| Locus: |
19p13, 3 |
| Discovery year: |
1991-03-04 |
| Entrez gene record: |
7409 |
| Pubmed identfication: |
9438848 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000181965 |