| Long name: |
Cy5, 5 Conjugated, ERK1+ERK2(T185+Y187+T202+Y204) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ERK1+ERK2 Thr185+Tyr187+Thr202+Tyr204 |
| Specificity: |
This is a highly specific antibody against ERK1+ERK2 Thr185+Tyr187+Thr202+Tyr204 |
| Modification: |
Phosphorylation |
| Modification site: |
Thr185+Tyr187+Thr202+Tyr204 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ERK1 around the phosphorylation site of Thr185/Tyr187+Thr202/Tyr204 |
| Gene ID number: |
5595 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Cell stimulation induces the activation of a signaling cascade, ERK1 and ERK2 are phosphorylated within the activation loop on both a Threonine and a Tyrosine residue (within a Thr-Glu-Tyr motif) by MEKs (MAPK/ERK kinases), These kinases belong to a family of serine/threonine kinases that are activated upon treatment of cells with a large variety of stimuli including mitogens, also known as MAPK (mitogen activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, and bioactive peptides, cytokines, growth factors, hormones, respectively, the downstream effects of which have been linked to the regulation of cell growth and differentiation as well as the cytoskeleton, thereby greatly elevating the activity of ERK1&, 2, ERK (extracellular signal regulated kinase) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
ERK1 p44mapk p44erk1 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
ERK1+ERK2(T185+Y187+T202+Y204) Conjugated |
| Short name: |
Conjugated, ERK1+ERK2(T185+Y187+T202+Y204) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, ERK1+ERK2(T185+Y187+T202+Y204) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6877 |
| Gene: |
MAPK3 |
More about : MAPK3 |
| Long gene name: |
mitogen-activated protein kinase 3 |
| Synonyms gene: |
PRKM3 |
| Locus: |
16p11, 2 |
| Discovery year: |
1993-11-05 |
| GenBank acession: |
M84490 |
| Entrez gene record: |
5595 |
| Pubmed identfication: |
9628824 |
| Classification: |
Mitogen-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000132149 |