Separase (Ser1073) Antibody

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Catalog number: bs-5304R
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: Separase (Ser1073) Antibody
Quantity: 0.1ml
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More details :

Long name: Separase (Ser1073) Primary Polyclonal Antibody
Also known as: Separase (Ser1073) PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: Separase Ser1073
Specificity: This is a highly specific antibody against Separase Ser1073
Modification(s): Phosphorylation
Modification site(s): Ser1073
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human ESPL1 around the phosphorylation site of Ser1073
Gene ID number: 9700
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: As the cellular division process continues, Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, Each cell must receive one chromatid of every chromosome, It not only cleaves cohesin at the onset of anaphase but also cleaves itself, Separase activity is highly regulated, Should a human cell become an aneuploid (one too many or too few chromatids), Should the embryo survive, allowing the chromatids to separate and divide with the cell, during mitosis, it will most likely develop severe birth defects or later develop malignant cancers, making certain that genomic information is replicated accurately, promoting downregulation of separase after anaphase, separase destroys cohesin by means of cleavage, the embryo most likely will not survive, Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: ESP 1, ESP-1, ESP1, ESPL 1, ESPL-1, ESPL1, ESPL1_HUMAN, Extra spindle poles like 1, Extra spindle poles like 1 protein, SSE, Separase, Separin, Similar to fission yeast cut1and gene, Caspase like protein ESPL1
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: Separase (Ser1073)
Short name: Separase (Ser1073) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: Separase (Ser1073) (Antibody to)
Alternative technique: antibodies

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