CDKN1A (Ser146) Antibody, ALEXA FLUOR 555

Catalog number:	bs-5239R-A555 Buy Now
Price:	489 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	CDKN1A (Ser146) Antibody, ALEXA FLUOR 555
Quantity:	100 microliters
Related search:	process biological protein kinase response regulation cell cellular activity cycle component negative serinethreonine complex the

More details Need more?:

Long name:	ALEXA FLUOR 555 Conjugated, CDKN1A (Ser146) Polyclonal Antibody
Also known as:	Anti-CDKN1A Ser146 PAb ALEXA FLUOR 555
Category:	Conjugated Primary Antibodies
Conjugated with:	555, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	CDKN1A Ser146
Specificity:	This is a highly specific antibody against CDKN1A Ser146
Modification:	Phosphorylation
Modification Site:	Ser146
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human CDKN1A around the phosphorylation site of Ser146 [QT(p-S)MT]
Gene ID Number:	1026
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, The expression of this gene is tightly controlled by the tumor suppressor protein p53, The p16INK4a family inhibits Cdk4 and Cdk6 specifically, The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition, This protein can interact with proliferating cell nuclear antigen (PCNA), This protein was reported to be specifically cleaved by CASP3-like caspases, Two alternatively spliced variants, Two families of cyclin dependent kinase inhibitors (CKIs) have been identified, a DNA polymerase accessory factor, and may be instrumental in the execution of apoptosis following caspase activation, and plays a regulatory role in S phase DNA replication and DNA damage repair, and thus functions as a regulator of cell cycle progression at G1, have been reported, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli, which encode an identical protein, which thus leads to a dramatic activation of CDK2, This gene encodes a potent cyclin-dependent kinase inhibitor
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	553nm/568nm
Synonyms:	P21 CIP1 WAF1 SDI1 CAP20 p21CIP1 p21Cip1/Waf1
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 555, Alexa Fluor
Gene target:	CDKN1A (Ser146)
Short name:	CDKN1A (Ser146) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 555
Alternative name:	ALEXA FLUOR 555, Cip1) (Ser146) (Antibody to), cyclin-dependent kinase inhibitor 1A (p21
Alternative technique:	antibodies
Alternative to gene target:	CAP20 and CDKN1 and CIP1 and MDA-6 and P21 and p21CIP1 and SDI1 and WAF1, CDKN1A and IDBG-630156 and ENSBTAG00000008353 and 513497, CDKN1A and IDBG-85033 and ENSG00000124762 and 1026, Cdkn1a and IDBG-159848 and ENSMUSG00000023067 and 12575, Cip1), metal ion binding, nuclei, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009411 and response to UV and biological process this GO :0009636 and response to toxic substance and biological process this GO :0010033 and response to organic substance and biological process this GO :0010165 and response to X-ray and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0019912 and cyclin-dependent protein kinase activating kinase activity and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0030332 and cyclin binding and molecular function this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031100 and organ regeneration and biological process this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0032403 and protein complex binding and molecular function this GO :0033158 and regulation of protein import into nucleus, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000307 and cyclin-dependent protein kinase holoenzyme complex and cellular component this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006977 and DNA damage response, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0019912 : cyclin-dependent protein kinase activating kinase activity and also this GO :0030332 : cyclin binding and also this GO :0032403 : protein complex binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0019912 : cyclin-dependent protein kinase activating kinase activity, this GO :0030332 : cyclin binding, this GO :0032403 : protein complex binding, this GO :0046872 : metal ion binding, translocation and biological process this GO :0034605 and cellular response to heat and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0042493 and response to drug and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043068 and positive regulation of programmed cell death and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045087 and innate immune response and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046685 and response to arsenic-containing substance and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051384 and response to glucocorticoid and biological process this GO :0051412 and response to corticosterone and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0055093 and response to hyperoxia and biological process this GO :0060574 and intestinal epithelial cell maturation and biological process this GO :0070557 and PCNA-p21 complex and cellular component this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0071850 and mitotic cell cycle arrest and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :0090398 and cellular senescence and biological process this GO :0090400 and stress-induced premature senescence and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :2000278 and regulation of DNA biosynthetic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, cyclin-dependent kinase inhibitor 1A (p21
Identity:	1784
Gene:	CDKN1A | More about : CDKN1A
Long gene name:	cyclin dependent kinase inhibitor 1A
Synonyms gene:	CDKN1
Synonyms gene name:	Cip1) , cyclin-dependent kinase inhibitor 1A (p21
Locus:	6p21, 2
Discovery year:	1994-05-24
GenBank acession:	U03106
Entrez gene record:	1026
RefSeq identity:	NM_078467
Havana BLAST/BLAT:	OTTHUMG00000014603

• #process
• #biological
• #protein
• #kinase
• #response
• #regulation
• #cell
• #cellular
• #activity
• #cycle
• #component
• #negative
• #serinethreonine
• #complex
• #the