| Long name: |
Bid (Ser61) Primary Polyclonal Antibody |
| Also known as: |
Bid (Ser61) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Bid Ser61 |
| Specificity: |
This is a highly specific antibody against Bid Ser61 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser61 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse Bid around the phosphorylation site of Ser61 |
| Gene ID number: |
12122 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas, Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, In animal model studies, Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway, Mutation in the SH3 domain can diminish the cytochrome c releasing activity, The cytochrome c releasing activity of Bid was antagonized by Bcl2, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor, which in turn induces cytochrome c release and mitochondrial damage, Bid |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AltName: BH3-interacting domain death agonist p15, BH3 interacting domain death agonist, BH3-interacting domain death agonist, BH3-interacting domain death agonist p11, BH3-interacting domain death agonist p13, BID, p-Bid phospho S61, p11 BID, p13 BID, p22 BID, Bid phospho S61 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Bid (Ser61) |
| Short name: |
Bid (Ser61) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BH3 interacting domain death a this GO nist (Ser61) (Antibody to) |
| Alternative technique: |
antibodies |